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For each session we have invited two leading scientists who will introduce the topic and present their perspective and relevant work. 

Abstract Submissions
Two to four additional speakers for each session will be selected from submitted abstracts.

Poster Sessions

The remainder of submitted abstracts will be presented as posters. Posters will be up throughout the meeting close to the lecture hall to ensure maximal exposure and optimally facilitate interactions.


We will organize “Career Lunch” (PhD students) with the speakers on Friday where PhD students meet with senior faculty.

Thursday, September 28


Registration & Coffee


Opening remarks - Welcome note


Session 1. Protein homeostasis 1
Chair: Ellen Nollen

  • 10:15-10:40
    Speakers: Alessandro Ori, Genentech, South San Francisco, USA / Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), Jena, Germany
    The aging brain proteome of a short-lived vertebrate

  • 10:40-10:55
    Milos Filipovic, Leibniz Institute for Analytical Sciences, ISAS, Berlin, Germany
    Age-induced thiol oxidation predisposes brain for neurodegeneration via aberrant phase separation




Session 1. Protein homeostasis 2

Chair: Ellen Nollen

  • 11:30-11:55
    Malene Hansen, The Buck Institute, Novato, USA
    Regulation of autophagy in aging and disease

  • 11:55-12:10​
    Paola Gallardo, ERIBA-UMCG, Groningen, The Netherlands
    Poor old Pores: Surveillance of intrinsically disordered nucleoporins

  • 12:10-12:25​
    Janine Kirstein, Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), Jena, Germany
    The role of chaperones in the phase-separation of Huntingtin




Chair: Cor Calkhoven

Session 2: Metabolism

  • 13:25-13:50
    Dudley Lamming, University of Wisconsin-Madison, USA
    When a calorie is not just a calorie: The regulation of health and longevity by dietary macronutrients

  • 13:50-14:15
    Peter Tessarz, Max Planck Institute for Biology of Ageing, Cologne, Germany
    Metabolism-epigenetics crosstalk in ageing

  • 14:-15-14:30
    Sanne Van der Rijt, Amsterdam UMC, The Netherlands
    Targeting phospholipid metabolism via Pla2g15 results in reduced senescence in murine kidney and increases longevity in C. elegans

  • 14:30-14:45
    Friedrich Becker, Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), Jena, Germany
    Dietary vitamin A restriction rescues declines in liver fat metabolism and ameliorates sarcopenia in aging mice 



Chair: Folkert Kuipers
Session 3: Gut microbiome

  • 15:15-15:40
    Sasha Zhernakova, University Medical Center Groningen, The Netherlands
    Biological aging markers in population cohorts - microbiome and more.

  • 15:40-15:55
    Aki Minoda, RIMLS, Radboud University Nijmegen, The Netherlands
    Mu-kin Mouse Ageing Atlas: How the microbiota affect ageing

  • 15:55-16:10
    Dennis De Bakker, Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), Jena, Germany 
    Microbiota transplantation can mitigate age-related brain inflammation and functional decline in a model of spontaneous Alzheimer’s-like pathology


Poster Session


Dinner at UMCG Fontein Patio



Keynote Lecture
Introduction: Cor Calkhoven

Michael Hall, Biozentrum, University of Basel, Switzerland
mTOR signaling in growth and metabolism


Reception at the City Hall invited by the Mayor of Groningen

Friday, September 29


Session 4. Senescence

Chair: Tamar Tchkonia

  • 9:00-9:25
    Marco Demaria, ERIBA-UMCG, Groningen, The Netherlands
    Purinergic signalling reinforces the production of SASP factors and promotes senescence-associated dysfunctions

  • 9:25-9:50
    Raffaella di Micco, I.R.C.C.S. Ospedale San Raffaele, Milano, Italy
    Exploiting senescence immunogenicity for leukemia treatment

  • 9:50-10:05​
    Akiko Mammoto, Medical College of Wisconsin, USA
    Endothelial senescence in hypoxia-induced lung vascular remodeling

  • 10:05-10:20
    Boshi Wang, ERIBA-UMCG, Groningen, The Netherlands
    Sex dimorphism in senescent cell turnover is mediated by FABP5



Coffee break

Session 5. Immune ageing
Chair: Claudia Waskow

  • 10:50-11:15
    Vishwa Deep Dixit, Yale School of Medicine, New Haven, USA
    Metabolic control of inflammaging

  • 11:15-11:40
    Mihai Netea, Radboud MC, Nijmegen, the Netherlands/ Limes, University of Bonn, Germany
    Impact of aging on trained immunity

  • 11:40-11:55
    Enric Urena Sala, University College London, UK
    Exploring the mechanisms of action of the life-extending drug trametinib in Drosophila

  • 11:55-12:10
    Patrick Schädel, Friedrich Schiller University, Jena, Germany
    Oxylipins as novel biomarkers of cellular and organismal inflammaging


Lunch and meet with the speakers (PhD students and Postdoc career advise)


Session 6. Stem cells and regeneration

Chair: Björn von Eyss

  • 13:30-13:55
    Maximina Yun, Center for Regenerative Therapies TU Dresden, Germany
    Towards uncovering the basis of negligible senescence in vertebrates: enter the salamander

  • 13:55-14:20
    Julia von Maltzahn, B-TU Cottbus-Senftenberg, Germany
    Muscle stem cells in age and disease

  • 14:20-14:35​
    Alberto Minetti, Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), Jena, Germany
    Proteostasis stress delays regeneration following injury in old small intestine epithelium 

  • 14:35-14:50
    Hugo Fernandes, University of Coimbra, Portugal
    Unlocking the regenerative potential of extracellular vesicles: Bioactivity enhancement through miRNA modulation



Coffee break


Session 7. DNA damage and genome regulation

Chair: Michael Chang

  • 15:20-15:45
    George Garinis, University of Crete, Greece
    DNA damage and innate immune responses during aging

  • 15:45-16:10
    Björn Schumacher, CECAD, University of Cologne, Germany
    Genome Stability in aging and inheritance: new insights from C. elegans

  • 16:10-16:25
    Rouven Arnold, SBP Medical Discovery Institute, La Jolla, USA
    Unraveling protective mechanisms of aging: A new role for histone chaperone HIRA

  • 16:25-16:40
    Mihailo Mirkovic, ETH, Zürich, Switzerland
    Introns drive asymmetric chromosome inheritance in ageing



Keynote Lecture
Introduction: Helen Morrison

Linda Partridge, UCL, London, UK
Ageing: a gut feeling


Dinner and party at the DOT – 10th anniversary ERIBA – B-flat Carpet Jazz Quintet – DJ – The Blues Cowboys

Saturday, September 30

Session 8. Organismal aging

Chair: Eugene Berezikov

  • 9:30-9:55
    Thomas Bosch, Christian Albrechts University of Kiel, Germany
    Longevity, cellular senescence and the microbiome - lessons from the non-senescent model Hydra

  • 9:55-10:10
    Johannes Krug, Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), Jena, Germany 
    The transparent klara line as a tool for in vivo analyses

Socioeconomic aspects of health and lifespan extension therapies Introduction: Ellen Nollen

Jochen Mierau, Lifelines, University of Groningen, The Netherlands

Coffee break


Keynote Lecture
Introduction: Folkert Kuipers

James (Jim) Kirkland, Mayo Clinic, Rochester, USA
Clinical studies of agents targeting aging mechanisms: the Translational Geroscience Network





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